Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855698 | 0.83 | DDB1 (0.51) | KMT2AMEN1L3MBTL1DDB1CRBN | |
| SCHEMBL4892237 | 0.82 | EPHX2 (0.45) | KMT2AMEN1EPHX2L3MBTL1DDB1 | |
| SCHEMBL3451882 | 0.74 | SIGMAR1 (0.54) | KMT2AL3MBTL1POLBGSK3AGSK3B | |
| SCHEMBL10417429 | 0.72 | L3MBTL1 (0.48) | KMT2AMEN1EPHX2L3MBTL1DDB1 | |
| SCHEMBL7745544 | 0.72 | EPHX2 (0.46) | KMT2AMEN1EPHX2L3MBTL1DDB1 | |
| SCHEMBL1488276 | 0.71 | L3MBTL1 (0.56) | KMT2AMEN1EPHX2L3MBTL1DDB1 | |
| SCHEMBL6853577 | 0.69 | GAA (0.50) | KMT2AMEN1DDB1CRBNCTSG | |
| SCHEMBL10649531 | 0.69 | EPHX2 (0.62) | KMT2AMEN1EPHX2L3MBTL1DDB1 | |
| SCHEMBL6855500 | 0.69 | DDB1 (0.54) | KMT2AMEN1L3MBTL1DDB1CRBN | |
| SCHEMBL7430313 | 0.68 | EPHX2 (0.49) | KMT2AMEN1EPHX2L3MBTL1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |