Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.45 |
| ▸ | THRB | P10828 | 7/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852992 | 0.90 | THRA (0.57) | THRATHRBMCL1 | |
| SCHEMBL6738420 | 0.85 | THRA (0.44) | THRATHRBL3MBTL1MMP2MMP9 | |
| SCHEMBL6853009 | 0.85 | THRA (0.45) | THRATHRBMMP2MMP1MMP3 | |
| SCHEMBL6735849 | 0.83 | THRA (0.50) | THRATHRB | |
| SCHEMBL6735850 | 0.83 | THRA (0.50) | THRATHRB | |
| SCHEMBL6854843 | 0.82 | THRA (0.41) | THRATHRBMCL1L3MBTL1 | |
| SCHEMBL6854274 | 0.82 | PPARA (0.41) | THRATHRBL3MBTL1 | |
| SCHEMBL6854726 | 0.81 | THRB (0.43) | THRATHRBL3MBTL1 | |
| SCHEMBL1642319 | 0.81 | THRA (0.59) | THRATHRB | |
| SCHEMBL4961754 | 0.81 | GAA (0.41) | THRATHRBL3MBTL1MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777442-B2 | Diphenyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | THRA 4665/4885THRB 4614/4885MCL1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.