Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992030 | 0.79 | CALM1 (0.52) | CALM1IDH1LTA4HTAAR1KDM5A | |
| SCHEMBL1563564 | 0.76 | CALM1 (0.48) | CALM1IDH1LTA4HTAAR1ROCK1 | |
| SCHEMBL1600990 | 0.76 | NOS3 (0.57) | CALM1IDH1LTA4HTAAR1NR3C2 | |
| SCHEMBL11159847 | 0.76 | CALM1 (0.48) | CALM1IDH1LTA4HTAAR1KDM4A | |
| SCHEMBL6949849 | 0.76 | LOXL2 (0.57) | CALM1IDH1LTA4HTAAR1CYP11B1 | |
| SCHEMBL24349558 | 0.76 | RECQL (0.57) | CALM1IDH1LTA4HTAAR1CYP11B1 | |
| SCHEMBL5521631 | 0.76 | KDM4E (0.52) | CALM1IDH1KDM4AKDM5AKDM4C | |
| SCHEMBL7247381 | 0.74 | CALM1 (0.46) | CALM1IDH1LTA4HTAAR1KDM5A | |
| SCHEMBL11630184 | 0.74 | CALM1 (0.46) | CALM1IDH1LTA4HTAAR1NR3C2 | |
| SCHEMBL5117845 | 0.74 | CALM1 (0.46) | CALM1IDH1LTA4HTAAR1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1238338-C | Process for the preparation of 4(5)-amino-5(4)carboxamidoimidoimidazoles and intermediates thereof | NIPPON SODA CO (JP) | 2006-01-25 | — | — | CN | disclosed |
| US-6797828-B1 | Processes for the preparation of 4(5)-amino-5(4)-carboxamidoimidazoles and intermediates thereof | NIPPON SODA CO. LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| CN-1502604-A | Process for the preparation of 4(5)-amino-5(4)carboxamidoimidoimidazoles and intermediates thereof | �ձ�������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1150169-C | Process for the preparation of 4(5) -amino-5 (4) -carbamoylimidazoles and intermediates thereof | �ձ�������ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1374951-A | Process for the preparation of 4(5) -amino-5 (4) -carbamoylimidazoles and intermediates thereof | NIPPON SODA CO (JP) | 2002-10-16 | — | — | CN | disclosed |
| EP-1215206-A1 | PROCESSES FOR THE PREPARATION OF 4(5)-AMINO-5(4)-CARBOXAMIDOIMIDAZOLES AND INTERMEDIATES THEREOF | NIPPON SODA CO., LTD. (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5670526-A | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |