SCHEMBL6949849

SCHEMBL6949849

Fc1cc(Cc2ccccc2)ccn1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.57
CALM1 P0DP23 1/20 0.48
CYP3A4 P08684 2/20 0.47
KCNQ2 O43526 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1A P35348 1/20 0.47
ADRA1B P35368 1/20 0.47
KCNH2 Q12809 1/20 0.47
KCNH3 Q9ULD8 2/20 0.44
IDH1 O75874 1/20 0.42
LTA4H P09960 2/20 0.41
TAAR1 Q96RJ0 1/20 0.40
CYP11B1 P15538 3/20 0.39
CYP11B2 P19099 3/20 0.39
CYP17A1 P05093 2/20 0.39
NR3C2 P08235 1/20 0.38
MAPK13 O15264 1/20 0.38
MAPK12 P53778 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8493165 0.84 LOXL2 (0.57) LOXL2CYP3A4KCNQ2ALOX15TSHR
SCHEMBL18711357 0.81 LOXL2 (0.53) LOXL2CYP3A4KCNQ2ALOX15TSHR
SCHEMBL4992030 0.79 CALM1 (0.52) LOXL2CALM1IDH1LTA4HTAAR1
SCHEMBL24852891 0.79 NR3C2 (0.51) LOXL2LTA4HTAAR1NR3C2MAPK14
SCHEMBL29452868 0.79 NR3C2 (0.51) LOXL2LTA4HTAAR1NR3C2MAPK14
SCHEMBL27341903 0.79 LOXL2 (0.47) LOXL2CYP3A4KCNQ2ALOX15TSHR
SCHEMBL1600990 0.76 NOS3 (0.57) CALM1CYP3A4KCNH3IDH1LTA4H
SCHEMBL6854720 0.76 CALM1 (0.48) CALM1TSHRADRA1DADRA1AADRA1B
SCHEMBL11159847 0.76 CALM1 (0.48) LOXL2CALM1TSHRADRA1DADRA1A
SCHEMBL24349558 0.76 RECQL (0.57) LOXL2CALM1CYP3A4ALOX15IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247276-B2 Micro-reactor for reactions between gases and liquids CELLULAR PROCESS CHEMISTRY, INC. (US) 2007-07-24 US disclosed
US-7247276-B2 Micro-reactor for reactions between gases and liquids CELLULAR PROCESS CHEMISTRY, INC. (US) 2007-07-24 US disclosed
EP-1349650-A2 MICRO-REACTOR FOR REACTIONS BETWEEN GASES AND LIQUIDS CPC Cellular Process Chemistry Systems GmbH (DE) 2003-10-08 EP disclosed
WO-2002009866-A2 MICRO-REACTOR FOR REACTIONS BETWEEN GASES AND LIQUIDS CPC - CELLULAR PROCESS CHEMISTRY SYSTEMS GMBH (DE) 2002-02-07 WO disclosed
WO-1989000560-A1 DIRECT FLUORINATION OF SUBSTITUTED PYRIDINES ALLIED SIGNAL INC (US) 1989-01-26 WO disclosed
US-4786733-A CONTACTING WITH FLUORINE GAS ALLIED-SIGNAL INC. (US) 1988-11-22 US disclosed