Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646183 | 0.81 | POLB (0.42) | POLBCD44ALDH1A1MAPTLMNA | |
| SCHEMBL31282761 | 0.79 | POLB (0.52) | POLBCD44ALDH1A1MAPTLMNA | |
| SCHEMBL2860306 | 0.79 | POLB (0.41) | POLBCD44ALDH1A1MAPTLMNA | |
| SCHEMBL8764611 | 0.79 | NPC1 (0.36) | CD44NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL16781740 | 0.76 | ALDH1A1 (0.32) | ALDH1A1HSD17B10CYP3A4TSHR | |
| SCHEMBL21614311 | 0.76 | CYP3A4 (0.40) | POLBCD44ALDH1A1MAPTLMNA | |
| SCHEMBL10745073 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MAPTLMNAHSD17B10GAA | |
| SCHEMBL175015 | 0.73 | ALDH1A1 (0.39) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL48465 | 0.73 | ALDH1A1 (0.39) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10572123 | 0.71 | NPC1 (0.38) | ALDH1A1HSD17B10HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780459-B2 | Method for stabilizing irregular structures | MACPHERSON SCOTT (CA) | 2004-08-24 | — | — | US | disclosed |
| US-20030022960-A1 | Method for stabilizing irregular structures | MACPHERSON SCOTT (CA) | 2003-01-30 | — | — | US | disclosed |
| WO-2001064603-A1 | METHOD FOR STABILIZING IRREGULAR STRUCTURES | MACPHERSON SCOTT (CA) | 2001-09-07 | — | — | WO | disclosed |