Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL8631065 | 0.98 | SLC6A2 (0.33) | CHRNB4CHRNA3SLC6A2HTTNR3C2 | |
| SCHEMBL6855484 | 0.90 | SLC6A2 (0.32) | CHRNB4CHRNA3SLC6A2ALKDRD3 | |
| Hydroxyamine SCHEMBL8631067 | 0.88 | SLC6A2 (0.31) | CHRNB4CHRNA3SLC6A2 | |
| SCHEMBL4013896 | 0.83 | SLC6A11 (0.41) | ALKSLC6A1 | |
| SCHEMBL31589135 | 0.83 | SLC6A11 (0.41) | ALKSLC6A1 | |
| SCHEMBL9908644 | 0.83 | SLC6A11 (0.41) | ALKSLC6A1 | |
| SCHEMBL3687661 | 0.83 | SLC6A11 (0.41) | ALKSLC6A1 | |
| SCHEMBL26315910 | 0.83 | SLC6A11 (0.41) | ALKSLC6A1 | |
| SCHEMBL8661014 | 0.73 | MAPT (0.38) | — | |
| SCHEMBL19463682 | 0.73 | SLC6A11 (0.43) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11920040-B2 | Carborhodamine compounds and methods of preparation thereof | ELITECHGROUP MDX LLC (US) | 2024-03-05 | — | — | US | disclosed |
| US-20230105320-A1 | CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF | ELITECHGROUP MDX LLC (US) | 2023-04-06 | — | — | US | disclosed |
| US-11618826-B2 | Carborhodamine compounds and methods of preparation thereof | ELITECHGROUP MDX LLC (US) | 2023-04-04 | — | — | US | disclosed |
| US-20220119424-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITechGroup MDX, LLC (US) | 2022-04-21 | — | — | US | disclosed |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20220002549-A1 | CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF | ELITECHGROUP, INC. (US) | 2022-01-06 | — | — | US | disclosed |
| US-11155713-B2 | Carborhodamine compounds and methods of preparation thereof | ELITECHGROUP, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| EP-3802526-A1 | CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF | ELITechGroup, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5714597-A | Use of carbocation scavenger during oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| US-5714606-A | OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| US-5698391-A | DETERMINATION OF TARGET PROPERTY; BIOSYNTHESIS CYCLES | ISIS PHARMACEUTICALS, INC. (US) | 1997-12-16 | — | — | US | disclosed |
| EP-0739335-A4 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS INC (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0739335-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| US-5519134-A | ANTIINFLAMMATORY AGENTS | ISIS PHARMACEUTICALS, INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5510476-A | SOLID PHASE SYNTHESIS USING AN ACIDIC SOLUTION OF THE SCAVENGER TO DEPROTECT THE 5'-HYDROXY AND NEUTRALIZE THE CARBO ANION RELEASED; HIGH YIELDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| WO-1995018792-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119424-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | CHRNB4 2432/4885CHRNA3 3369/4885SLC6A2 321/4885 |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | CHRNB4 2432/4885CHRNA3 3369/4885SLC6A2 321/4885 |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | CHRNB4 2432/4885CHRNA3 3369/4885SLC6A2 321/4885 |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | CHRNB4 2432/4885CHRNA3 3369/4885SLC6A2 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.