SCHEMBL4013896

SCHEMBL4013896

COc1ccc(C(OC[C@@H]2C[C@@H](O)CN2)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.41
SLC6A1 P30531 2/20 0.41
TYMP P19971 1/20 0.40
KIF11 P52732 7/20 0.36
KCNH2 Q12809 1/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC6A12 P48065 1/20 0.36
SLC6A13 Q9NSD5 1/20 0.36
ALK Q9UM73 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687661 1.00 SLC6A11 (0.41) SLC6A11SLC6A1TYMPKIF11KCNH2
SCHEMBL9908644 1.00 SLC6A11 (0.41) SLC6A11SLC6A1TYMPKIF11KCNH2
SCHEMBL26315910 1.00 SLC6A11 (0.41) SLC6A11SLC6A1TYMPKIF11KCNH2
SCHEMBL31589135 1.00 SLC6A11 (0.41) SLC6A11SLC6A1TYMPKIF11KCNH2
SCHEMBL19463682 0.89 SLC6A11 (0.43) SLC6A11SLC6A1TYMPKIF11KCNH2
SCHEMBL20414094 0.88 SLC6A11 (0.43) SLC6A11SLC6A1TYMPKIF11KCNH2
SCHEMBL6855480 0.83 CHRNB4 (0.34) SLC6A1ALK
Hydroxyamine SCHEMBL8631065 0.81 SLC6A2 (0.33) ALK
SCHEMBL6855484 0.81 SLC6A2 (0.32) ALK
Hydroxyamine SCHEMBL8631067 0.79 SLC6A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745238-A1 OLIGONUCLEOTIDE TARGETING ANGIOTENSINOGEN AND USE THEREOF Anlong Biopharmaceutical Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025264952-A2 NOVEL RNA THERAPEUTICS AND USES THEREOF ELI LILLY AND COMPANY (US) 2025-12-26 WO disclosed
CN-119998450-A Oligonucleotide targeting angiotensinogen and application thereof 北京安龙生物医药有限公司 2025-05-13 CN disclosed
CN-119925624-A Liver targeting compound and conjugate, preparation method and application thereof 上海数因信科智能科技有限公司 2025-05-06 CN disclosed
WO-2025087442-A1 OLIGONUCLEOTIDE TARGETING LIPOPROTEIN A AND USE THEREOF 北京安龙生物医药有限公司 2025-05-01 WO disclosed
WO-2025077916-A1 TRANSTHYRETIN-TARGETING OLIGONUCLEOTIDE AND USE THEREOF 北京安龙生物医药有限公司 2025-04-17 WO disclosed
WO-2025021829-A1 MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF ASTRAZENECA AB (SE) 2025-01-30 WO disclosed
WO-2025016342-A1 OLIGONUCLEOTIDE TARGETING ANGIOTENSINOGEN AND USE THEREOF 北京安龙生物医药有限公司 2025-01-23 WO disclosed
CN-118993970-A Preparation method of L96 side chain compound 苏州富士莱医药股份有限公司 2024-11-22 CN disclosed
CN-118206597-A GalNAc-siRNA conjugate structure and application thereof 北京安龙生物医药有限公司 2024-06-18 CN disclosed
EP-1991705-A4 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES INC (US) 2009-07-01 EP disclosed
EP-1991705-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING Epoch Biosciences, Inc. (US) 2008-11-19 EP disclosed
EP-1466176-A4 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES INC (US) 2008-10-01 EP disclosed
WO-2007098336-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2007-08-30 WO disclosed
US-20060204990-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2006-09-14 US disclosed
US-20050277144-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-12-15 US disclosed
US-6972339-B2 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-12-06 US disclosed
US-20050176066-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-08-11 US disclosed
EP-1466176-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING Epoch Biosciences, Inc. (US) 2004-10-13 EP disclosed
WO-2003023357-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2003-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050176066-A1 Compounds and methods for fluorescent labeling HLCS, GLB1, TUBB SLC6A11 1989/4885SLC6A1 1684/4885TYMP 466/4885
US-20060204990-A1 Compounds and methods for fluorescent labeling GLB1, HLCS, PFAS SLC6A11 1325/4885SLC6A1 1057/4885TYMP 238/4885
US-20050277144-A1 Compounds and methods for fluorescent labeling HLCS, GLB1, TUBB SLC6A11 1989/4885SLC6A1 1684/4885TYMP 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.