Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942319 | 0.89 | TEAD3 (0.56) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL22440218 | 0.85 | LTA4H (0.77) | TEAD3LTA4HHRH3SIGMAR1KDM4E | |
| SCHEMBL8109363 | 0.85 | LTA4H (0.55) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL6947336 | 0.85 | LTA4H (0.55) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL17284609 | 0.84 | LTA4H (0.61) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL6943888 | 0.84 | LTA4H (0.54) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL6947688 | 0.84 | LTA4H (0.54) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL8115844 | 0.84 | LTA4H (0.54) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL7395255 | 0.83 | TEAD3 (0.59) | TEAD3LTA4HHRH3TMEM97SIGMAR1 | |
| SCHEMBL21310157 | 0.82 | BCHE (0.55) | TEAD3HRH3TMEM97SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |