Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855500 | 0.83 | DDB1 (0.54) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL6858115 | 0.83 | KMT2A (0.44) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL6854285 | 0.76 | ALDH1A1 (0.44) | L3MBTL1KMT2APOLBMEN1CYP2D6 | |
| SCHEMBL7389188 | 0.73 | L3MBTL1 (0.73) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL6856024 | 0.71 | DDB1 (0.47) | DDB1CRBNKMT2AMEN1GAA | |
| SCHEMBL8248998 | 0.70 | DDB1 (0.59) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL4892237 | 0.69 | EPHX2 (0.45) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL29450073 | 0.69 | KMT2A (0.76) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL16416392 | 0.69 | KMT2A (0.76) | DDB1CRBNL3MBTL1KMT2APOLB | |
| SCHEMBL11052192 | 0.69 | KMT2A (0.59) | DDB1CRBNL3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |