SCHEMBL6856086

SCHEMBL6856086

[O]S(=O)(=O)c1cc(O)ccc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.63
GAA P10253 3/20 0.57
POLB P06746 2/20 0.57
GFER P55789 1/20 0.57
ALPL P05186 1/20 0.55
ALPI P09923 1/20 0.55
ALPG P10696 1/20 0.55
DNMT1 P26358 1/20 0.55
MCL1 Q07820 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
LMNA P02545 2/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 1/20 0.52
HIF1A Q16665 1/20 0.52
ALDH1A1 P00352 3/20 0.50
PKM P14618 1/20 0.50
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900962 0.83 ALPL (0.74) PTGS1GAAPOLBGFERALPL
SCHEMBL30678705 0.83 ALPL (0.74) PTGS1GAAPOLBGFERALPL
Dobesilic Acid SCHEMBL29389625 0.81 LMNA (0.72) PTGS1GAAPOLBGFERALPL
SCHEMBL27802082 0.81 PTGS1 (0.63) PTGS1GAAPOLBGFERALPL
Dobesilic Acid SCHEMBL232087 0.81 LMNA (0.72) PTGS1GAAPOLBGFERALPL
SCHEMBL6858853 0.81 PDK2 (0.49) PTGS1GAAPOLBGFERALPL
Dobesilic Acid SCHEMBL10589964 0.79 HSD17B10 (0.70) PTGS1GAAPOLBGFERALPL
Dobesilic Acid SCHEMBL370202 0.79 LMNA (0.70) PTGS1GAAPOLBGFERALPL
Dobesilic Acid SCHEMBL866670 0.79 LMNA (0.70) PTGS1GAAPOLBGFERALPL
Dobesilic Acid SCHEMBL78222 0.79 LMNA (0.70) PTGS1GAAPOLBGFERALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783913-B2 POLYMERIC ACETAL RESIN CONTAINS UNITS (A), (B), (C), (D), AND (E). UNIT (A) IS A VINYL ALCOHOL UNIT. UNIT; (B) IS A POLYVINYL ACETAL UNIT CONTAINING AN R GROUP, WHERE R IS HYDROGEN, AN ALIPHATIC GROUP, AN AROMATIC GROUP, OR AN KODAK POLYCHROME GRAPHICS LLC 2004-08-31 US claimed
US-20030198887-A1 Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing EASTMAN KODAK COMPANY 2003-10-23 US claimed