SCHEMBL6856738

SCHEMBL6856738

Nc1cc(Oc2c(F)c(F)c(-c3c(F)c(F)c(Oc4ccc(O)c(N)c4)c(F)c3F)c(F)c2F)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.49
MAPT P10636 7/20 0.49
GAA P10253 7/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
THRB P10828 4/20 0.49
KDM4E B2RXH2 3/20 0.49
RECQL P46063 2/20 0.49
BLM P54132 1/20 0.49
MCL1 Q07820 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HSP90AA1 P07900 2/20 0.46
POLB P06746 2/20 0.46
NR4A1 P22736 1/20 0.39
HSD17B10 Q99714 6/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
ALOX15 P16050 3/20 0.37
ALOX12 P18054 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852477 0.95 MAPT (0.45) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL7719544 0.95 ALDH1A1 (0.53) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL28464375 0.92 MAPT (0.45) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL4622978 0.86 MAPT (0.46) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL6853365 0.84 MAPT (0.44) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL19990153 0.82 ALDH1A1 (0.40) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL6849207 0.82 MAPT (0.42) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL6854236 0.81 HSD17B10 (0.41) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL7714315 0.80 MAPT (0.50) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL29462465 0.79 ALDH1A1 (0.65) ALDH1A1MAPTGAASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
US-20210309866-A1 LIQUID COMPOSITION, QUANTUM DOT-CONTAINING FILM, OPTICAL FILM, LIGHT-EMITTING DISPLAY ELEMENT PANEL, AND LIGHT-EMITTING DISPLAY DEVICE TOKYO OHKA KOGYO CO., LTD. (JP) 2021-10-07 US disclosed
EP-3812805-A1 LIQUID COMPOSITION, QUANTUM DOT-CONTAINING FILM, OPTICAL FILM, LUMINESCENT DISPLAY ELEMENT PANEL, AND LUMINESCENT DISPLAY DEVICE TOKYO OHKA KOGYO CO., LTD. (JP) 2021-04-28 EP disclosed
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 US disclosed
US-10570269-B2 Composition containing microparticles TOKYO OHKA KOGYO CO., LTD. (JP) 2020-02-25 US disclosed
EP-3275940-B1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2019-12-18 EP disclosed
US-20190225804-A1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-25 US disclosed
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-12 US disclosed
US-9890250-B2 Method for producing polybenzoxazole resin TOKYO OHKA KOGYO CO., LTD. (JP) 2018-02-13 US disclosed
EP-3275940-A1 ENERGY-SENSITIVE RESIN COMPOSITION Tokyo Ohka Kogyo Co., Ltd. (JP) 2018-01-31 EP disclosed
US-20170115563-A1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2017-04-27 US disclosed
US-9410055-B2 Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-08-09 US disclosed
US-20150337084-A1 METHOD FOR PRODUCING POLYBENZOXAZOLE RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2015-11-26 US disclosed
EP-2947112-A1 METHOD FOR PRODUCING POLYBENZOXAZOLE RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2015-11-25 EP disclosed
EP-2695906-A1 POLYBENZOXAZOLE RESIN AND PRECURSOR THEREOF Mitsubishi Gas Chemical Company, Inc. (JP) 2014-02-12 EP disclosed
US-20130324662-A1 POLYBENZOXAZOLE RESIN AND PRECURSOR THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-12-05 US disclosed
US-6780561-B2 FOR FORMING PROTECTIVE FILM OR AN INSULATING FILM FOR A SEMICONDUCTOR ELEMENT OR A CIRCUIT BOARD SUCH AS A PRINTED BOARD KANSAI PAINT CO., LTD. (JP) 2004-08-24 US disclosed
US-20030143480-A1 For forming protective film or an insulating film for a semiconductor element or a circuit board such as a printed board KANSAI PAINT CO., LTD. (JP) 2003-07-31 US disclosed
US-6380271-B1 MIXING A POLYBENZOXAZOLE PRECURSOR OR A POLYBENZOXAZOLE RESIN WITH AN OLIGOMER, FORMING FILM FROM RESULTING MIXTURE, HEATING FILM IN NITROGEN CONTAINING OXYGEN TO GIVE RISE TO THERMAL DECOMPOSITION AND GASIFICATION OF OLIGOMER TO FORM RESIN LAYER SUMITOMO BAKELITE COMPANY LIMITED (JP) 2002-04-30 US disclosed
US-6297351-B1 EXCELLENT IN ELECTRIC CHARACTERISTICS AND HEAT RESISTANCE, PRECURSOR FROM A DICARBOXYLIC ACID AND A BISAMINOPHENOL COMPOUND OR A DIAMINODIHYDROXY SUMITOMO BAKELITE COMPANY LIMITED (JP) 2001-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES CHMP4B, EXOSC10, EXOSC9 ALDH1A1 1737/4885MAPT 35/4885GAA 1879/4885
US-10570269-B2 Composition containing microparticles CHMP4B, EXOSC10, EXOSC9 ALDH1A1 1737/4885MAPT 35/4885GAA 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.