SCHEMBL4622978

SCHEMBL4622978

Nc1ccc(Oc2c(F)c(F)c(-c3c(F)c(F)c(Oc4ccc(N)c(O)c4)c(F)c3F)c(F)c2F)cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.46
POLB P06746 3/20 0.46
HSP90AA1 P07900 1/20 0.46
HSD17B10 Q99714 3/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
NR4A1 P22736 1/20 0.39
MMP2 P08253 1/20 0.38
MMP14 P50281 1/20 0.38
KDM4E B2RXH2 3/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
GAA P10253 2/20 0.36
RAB9A P51151 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6849207 0.95 MAPT (0.42) MAPTPOLBHSP90AA1HSD17B10CYP3A4
SCHEMBL7714315 0.95 MAPT (0.50) MAPTPOLBHSP90AA1HSD17B10CYP3A4
SCHEMBL7658168 0.87 HPGD (0.50) MAPTPOLBHSP90AA1HSD17B10MMP2
SCHEMBL6856738 0.86 ALDH1A1 (0.49) MAPTPOLBHSP90AA1HSD17B10ALOX15
SCHEMBL7551329 0.85 MAPT (0.42) MAPTPOLBHSP90AA1HSD17B10CYP3A4
SCHEMBL4623369 0.84 MAPT (0.41) MAPTPOLBHSP90AA1HSD17B10CYP3A4
SCHEMBL6852477 0.82 MAPT (0.45) MAPTPOLBHSP90AA1HSD17B10ALOX15
SCHEMBL4624402 0.82 MAPT (0.40) MAPTPOLBHSP90AA1HSD17B10CYP3A4
SCHEMBL17267847 0.81 HSD17B10 (0.41) MAPTPOLBHSP90AA1HSD17B10CYP3A4
SCHEMBL7719544 0.80 ALDH1A1 (0.53) MAPTPOLBHSP90AA1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11189573-A None JP disclosed
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
US-20210309866-A1 LIQUID COMPOSITION, QUANTUM DOT-CONTAINING FILM, OPTICAL FILM, LIGHT-EMITTING DISPLAY ELEMENT PANEL, AND LIGHT-EMITTING DISPLAY DEVICE TOKYO OHKA KOGYO CO., LTD. (JP) 2021-10-07 US disclosed
EP-3812805-A1 LIQUID COMPOSITION, QUANTUM DOT-CONTAINING FILM, OPTICAL FILM, LUMINESCENT DISPLAY ELEMENT PANEL, AND LUMINESCENT DISPLAY DEVICE TOKYO OHKA KOGYO CO., LTD. (JP) 2021-04-28 EP disclosed
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 US disclosed
US-10570269-B2 Composition containing microparticles TOKYO OHKA KOGYO CO., LTD. (JP) 2020-02-25 US disclosed
EP-3275940-B1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2019-12-18 EP disclosed
US-20190225804-A1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-25 US disclosed
US-10023540-B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-17 US disclosed
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-12 US disclosed
US-20150337084-A1 METHOD FOR PRODUCING POLYBENZOXAZOLE RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2015-11-26 US disclosed
EP-2947112-A1 METHOD FOR PRODUCING POLYBENZOXAZOLE RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2015-11-25 EP disclosed
EP-0905169-B1 Precursors of polybenzoxazoles and polybenzothiazoles INFINEON TECHNOLOGIES AG (DE) 2008-04-02 EP disclosed
US-6380271-B1 MIXING A POLYBENZOXAZOLE PRECURSOR OR A POLYBENZOXAZOLE RESIN WITH AN OLIGOMER, FORMING FILM FROM RESULTING MIXTURE, HEATING FILM IN NITROGEN CONTAINING OXYGEN TO GIVE RISE TO THERMAL DECOMPOSITION AND GASIFICATION OF OLIGOMER TO FORM RESIN LAYER SUMITOMO BAKELITE COMPANY LIMITED (JP) 2002-04-30 US disclosed
US-6297351-B1 EXCELLENT IN ELECTRIC CHARACTERISTICS AND HEAT RESISTANCE, PRECURSOR FROM A DICARBOXYLIC ACID AND A BISAMINOPHENOL COMPOUND OR A DIAMINODIHYDROXY SUMITOMO BAKELITE COMPANY LIMITED (JP) 2001-10-02 US disclosed
US-6156902-A Bis-o-amino (thio) phenols, and their preparation INFINEON TECHNOLOGIES AG (DE) 2000-12-05 US disclosed
US-6153350-A Polybenzoxazole and polybenzothiazole precursors SIEMENS AKTIENGESELLSCHAFT (DE) 2000-11-28 US disclosed
JP-H11189573-A BIS-O-AMINO(THIO)PHENOL AND ITS PRODUCTION SIEMENS AG 1999-07-13 JP disclosed
EP-0918050-A1 Bis-o-amino(thio)phenols and their preparation SIEMENS AKTIENGESELLSCHAFT (DE) 1999-05-26 EP disclosed
EP-0905169-A2 Precursors of polybenzoxazoles and polybenzothiazoles SIEMENS AKTIENGESELLSCHAFT (DE) 1999-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES CHMP4B, EXOSC10, EXOSC9 MAPT 35/4885POLB 806/4885HSP90AA1 62/4885
US-10023540-B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element SLC9A2, SLC9A1, NHERF1 MAPT 2522/4885POLB 2120/4885HSP90AA1 206/4885
US-10570269-B2 Composition containing microparticles CHMP4B, EXOSC10, EXOSC9 MAPT 35/4885POLB 806/4885HSP90AA1 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.