Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857026 | 0.84 | AVPR1B (0.48) | — | |
| SCHEMBL6856769 | 0.84 | KMO (0.39) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL6856938 | 0.84 | PTGDR2 (0.44) | RXRARXRBKDM4ECSNK2A2CSNK2B | |
| SCHEMBL10102664 | 0.82 | KDM4E (0.50) | KDM4EMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL6857165 | 0.79 | KDM4E (0.51) | RXRARXRBRXRGKDM4EMEN1 | |
| SCHEMBL10509302 | 0.72 | KDM4E (0.65) | KDM4EMEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL3384876 | 0.72 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6857065 | 0.69 | AVPR1B (0.45) | AVPR1A | |
| SCHEMBL6857380 | 0.69 | TRPV1 (0.38) | KDM4E | |
| SCHEMBL6857381 | 0.69 | MDM2 (0.40) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |