Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856809 | 0.84 | MTNR1A (0.36) | KMOICMTCASP3TSPOCTSA | |
| SCHEMBL6857380 | 0.84 | TRPV1 (0.38) | ICMTCTSAKDM4E | |
| SCHEMBL6857381 | 0.84 | MDM2 (0.40) | ICMTMDM2 | |
| SCHEMBL6856940 | 0.84 | RXRA (0.41) | KMOPTGDR2TBXA2RPTGDRKDM4E | |
| SCHEMBL6856237 | 0.82 | KMO (0.42) | KMOADORA2AADORA1DGAT1RPA1 | |
| SCHEMBL6856907 | 0.81 | LMNA (0.43) | KMOPTGDR2MDM2CASP3TSPO | |
| SCHEMBL6856938 | 0.75 | PTGDR2 (0.44) | ADORA2APTGDR2KDM4EALDH1A1 | |
| SCHEMBL6856613 | 0.75 | HRH3 (0.48) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL10102664 | 0.73 | KDM4E (0.50) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6856772 | 0.72 | MTNR1A (0.36) | KMOCASP3TSPOKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |