Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 10/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857475 | 0.85 | AVPR1B (0.54) | AVPR1B | |
| SCHEMBL6856966 | 0.85 | PTGES (0.39) | AVPR1BPTGESMAOB | |
| SCHEMBL6857173 | 0.85 | AVPR1B (0.45) | AVPR1B | |
| SCHEMBL6857216 | 0.82 | AVPR1B (0.49) | SMN1; SMN2AVPR1BPDE3BPDE3AP2RY12 | |
| SCHEMBL6856761 | 0.77 | AVPR1B (0.41) | AVPR1BPDE3BPDE3AP2RY12 | |
| SCHEMBL6856187 | 0.73 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL6857205 | 0.71 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL6855518 | 0.70 | AVPR1B (0.66) | AVPR1B | |
| SCHEMBL6857155 | 0.69 | AVPR1B (0.56) | AVPR1B | |
| SCHEMBL6857161 | 0.69 | AVPR1B (0.43) | SMN1; SMN2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |