Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 14/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857173 | 0.92 | AVPR1B (0.45) | AVPR1BHRH3 | |
| SCHEMBL6856961 | 0.85 | SMN1; SMN2 (0.39) | AVPR1B | |
| SCHEMBL6855518 | 0.84 | AVPR1B (0.66) | AVPR1BHRH3 | |
| SCHEMBL16423582 | 0.80 | AVPR1B (0.61) | AVPR1BHRH3 | |
| SCHEMBL6856187 | 0.80 | AVPR1B (0.65) | AVPR1BHRH3 | |
| SCHEMBL6856988 | 0.80 | AVPR1B (0.53) | AVPR1BHRH3MIFATM | |
| SCHEMBL6856966 | 0.78 | PTGES (0.39) | AVPR1B | |
| SCHEMBL6857205 | 0.77 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL6857155 | 0.76 | AVPR1B (0.56) | AVPR1B | |
| SCHEMBL16442055 | 0.75 | AVPR1B (0.55) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |