SCHEMBL6856973

SCHEMBL6856973

O=P(O)(O)OP(=O)(O)OP(O)(=S)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
BTN3A1 O00481 3/20 0.35
ENPP1 P22413 1/20 0.33
MVD P53602 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2457997 0.90 FDPS (0.43) FDPSBLMTDP1BTN3A1ENPP1
SCHEMBL936042 0.88 FDPS (0.60) FDPSBLMTDP1BTN3A1
SCHEMBL5134982 0.85 FDPS (0.39) FDPSBLMTDP1BTN3A1ENPP1
Triphosphate SCHEMBL15270533 0.85 FDPS (0.56) FDPSBLMTDP1BTN3A1ENPP1
SCHEMBL13184011 0.82 FDPS (0.41) FDPSBLMTDP1BTN3A1MVD
SCHEMBL13183948 0.82 FDPS (0.41) FDPSBLMTDP1BTN3A1
Triphosphate SCHEMBL18714 0.82 FDPS (0.69) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL15555988 0.82 FDPS (0.69) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL29692 0.80 FDPS (0.50) FDPSBLMTDP1BTN3A1ENPP1
SCHEMBL15239278 0.80 FDPS (0.50) FDPSBLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425499-A Methods of treating myotonic muscular dystrophy type 1 using peptide-oligonucleotide conjugates 肽世代公司 2024-01-19 CN disclosed
CN-117295525-A Cell penetrating peptide conjugates and methods of use thereof 牛津大学科技创新有限公司 2023-12-26 CN disclosed
CN-108025017-A MiR-19 conditioning agents and application thereof 米拉根医疗股份有限公司 2018-05-11 CN disclosed
US-6828148-B2 Compound for use in the treatment of infections, arthritis, artherosclerosis, restenosis, psoriasis, cancer and leukemia GENE SHEARS PTY. LIMITED (AU) 2004-12-07 US disclosed
US-20020155454-A1 Miniribozymes active at low magnesium ion concentrations GENE SHEARS PTY. LIMITED (AU) 2002-10-24 US disclosed
WO-2000039146-A1 MINIRIBOZYMES ACTIVE AT LOW MAGNESIUM ION CONCENTRATIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155454-A1 Miniribozymes active at low magnesium ion concentrations EMG1, RNASE1, MMEL1 FDPS 2776/4885BLM 1676/4885TDP1 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.