SCHEMBL685783

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11760568	1.00	TYR (0.50)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL685057	0.98	TYR (0.47)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL5375049	0.93	TYR (0.47)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL11410036	0.87	TYR (0.63)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL1823735	0.87	TYR (0.53)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL1823738	0.87	TYR (0.53)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL5372285	0.86	TRPA1 (0.49)	ALOX5TRPA1
	SCHEMBL1823336	0.85	TYR (0.50)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL1823337	0.85	TYR (0.50)	TYRMEN1TP53CYP3A4ALOX5
	SCHEMBL12802075	0.85	TYR (0.46)	TYRMEN1TP53CYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.