Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL995806 | 0.96 | GPR3 (0.34) | GPR3POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL6862745 | 0.96 | GPR3 (0.34) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL7510367 | 0.96 | GPR3 (0.36) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL540904 | 0.95 | GPR3 (0.35) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL28790426 | 0.91 | GPR3 (0.33) | GPR3POLBKMT2AMEN1ATM | |
| SCHEMBL29171300 | 0.90 | GPR3 (0.32) | GPR3POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL8022568 | 0.82 | GAA (0.30) | GAA | |
| Hydrochloric Acid SCHEMBL4489415 | 0.82 | — | — | |
| SCHEMBL7630038 | 0.81 | — | — | |
| SCHEMBL4480345 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004044018-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED DIENES AND IN SITU FORMATION OF POLYMER BLENDS AND PRODUCTS MADE THEREBY | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-05-27 | — | — | WO | disclosed |