SCHEMBL7510367

SCHEMBL7510367

CC(C)(C)N[Si](C)(C)C1c2ccccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.36
POLB P06746 3/20 0.33
KMT2A Q03164 3/20 0.33
ACHE P22303 3/20 0.33
BCHE P06276 2/20 0.33
MEN1 O00255 2/20 0.33
ATM Q13315 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
NCOR2 Q9Y618 1/20 0.32
HTR2A P28223 1/20 0.32
PBRM1 Q86U86 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540904 0.98 GPR3 (0.35) GPR3POLBKMT2AACHEBCHE
Hydrochloric Acid SCHEMBL995806 0.96 GPR3 (0.34) GPR3POLBKMT2AACHEBCHE
Hydrochloric Acid SCHEMBL6858048 0.96 GPR3 (0.34) GPR3POLBKMT2AACHEBCHE
Hydrochloric Acid SCHEMBL6862745 0.96 GPR3 (0.34) GPR3POLBKMT2AACHEBCHE
SCHEMBL28790426 0.95 GPR3 (0.33) GPR3POLBKMT2AACHEBCHE
SCHEMBL29171300 0.93 GPR3 (0.32) GPR3POLBKMT2AACHEBCHE
SCHEMBL7630038 0.84
Hydrochloric Acid SCHEMBL8022568 0.82 GAA (0.30)
SCHEMBL4480345 0.81
SCHEMBL6908346 0.80 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179914-A1 METHOD FOR PRODUCING CATALYST POLYPLASTICS CO., LTD. (JP) 2020-06-11 US disclosed
EP-1070072-A4 SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS BOULDER SCIENT CO (US) 2002-09-25 EP disclosed
EP-1150986-A4 SILYL AMINES BOULDER SCIENT CO (US) 2002-08-07 EP disclosed
US-6410767-B2 USING N-SILYLATED MONO(CYCLOPENTADIENYL) LIGAND BOULDER SCIENTIFIC CO. 2002-06-25 US disclosed
US-20010056199-A1 Silylated and N-silylated compound synthesis BOULDER SCIENTIFIC COMPANY 2001-12-27 US disclosed
EP-1150986-A1 SILYL AMINES BOULDER SCIENTIFIC COMPANY (US) 2001-11-07 EP disclosed
WO-2001038334-A1 SILYL AMINES BOULDER SCIENTIFIC COMPANY (US) 2001-05-31 WO disclosed
US-6180810-B1 SILYL AMINES WHICH BOND COVALENTLY TO METAL CENTER OF COMPLEX TO PROVIDE OLEFIN POLYMERIZATION CATALYST COMPONENT BOULDER SCIENTIFIC COMPANY 2001-01-30 US disclosed
EP-1070072-A1 SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS BOULDER SCIENTIFIC COMPANY (US) 2001-01-24 EP disclosed
WO-2000047587-A1 SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS BOULDER SCIENTIFIC COMPANY (US) 2000-08-17 WO disclosed
US-6087518-A Silylated and N-silylated compound synthesis BOULDER SCIENTIFIC COMPANY (US) 2000-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056199-A1 Silylated and N-silylated compound synthesis LSS, NCL, FNTA GPR3 2349/4885POLB 3911/4885KMT2A 1469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.