Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.43 |
| ▸ | CTSK | P43235 | 16/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853698 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6849919 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6858021 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6855617 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6849865 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6849864 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6855613 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6849913 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6857959 | 0.99 | CTSS (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6857993 | 0.99 | CTSS (0.42) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317420-A1 | 2-AMINO-2-ALKYL-3 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | claimed |
| US-20020072631-A1 | 2-amino-2-alkyl-3 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors | PHARMACIA CORLPORATION | 2002-06-13 | — | — | US | claimed |
| WO-2002022561-A1 | 2-AMINO-2-ALKYL-3 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |
| US-6828456-B2 | Therapy | PHARMACIA CORPORATION | 2004-12-07 | — | — | US | disclosed |
| EP-1317420-A1 | 2-AMINO-2-ALKYL-3 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| US-20020072631-A1 | 2-amino-2-alkyl-3 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors | PHARMACIA CORLPORATION | 2002-06-13 | — | — | US | disclosed |
| WO-2002022561-A1 | 2-AMINO-2-ALKYL-3 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072631-A1 | 2-amino-2-alkyl-3 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors | NOS3, ALOX12, ALOX5 | CTSS 2686/4885CTSK 3697/4885CTSL 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.