SCHEMBL6858574

SCHEMBL6858574

C[C@@H](OP(=O)(O)OC(=O)[C@@H](N)CCC(N)=O)[C@H](N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 6/20 0.44
P2RY10 O00398 5/20 0.44
ALOX15 P16050 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
KMT2A Q03164 1/20 0.44
DPP4 P27487 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
LAP3 P28838 2/20 0.32
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
GRM7 Q14831 1/20 0.31
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL6864537 0.82 ALOX15 (0.56) GPR174P2RY10ALOX15BLMPMP22
SCHEMBL28135591 0.78 ALOX15 (0.44) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2482058 0.78 ALOX15 (0.53) GPR174P2RY10ALOX15BLMPMP22
SCHEMBL6858569 0.76 ALOX15 (0.51) GPR174P2RY10ALOX15BLMPMP22
SCHEMBL27986531 0.75 ALOX15 (0.44) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28137272 0.74 ALOX15 (0.50) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2351136 0.74 ALOX15 (0.50) ALOX15BLMPMP22KMT2ADPP4
Asparagine SCHEMBL6130108 0.72 ALOX15 (0.50) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28919279 0.71 ALOX15 (0.47) ALOX15BLMPMP22KMT2ADPP4
Cysteine SCHEMBL8071966 0.71 ALOX15 (0.49) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6803203-B1 PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS BROOKHAVEN SCIENCE ASSOCIATES 2004-10-12 US disclosed