SCHEMBL6858569

SCHEMBL6858569

NC(=O)CC[C@H](N)C(=O)OP(=O)(O)OC[C@H](N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.51
BLM P54132 1/20 0.51
PMP22 Q01453 1/20 0.51
KMT2A Q03164 1/20 0.51
P2RY10 O00398 15/20 0.44
GPR34 Q9UPC5 8/20 0.44
GPR174 Q9BXC1 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dexfosfoserine SCHEMBL6864340 0.81 ALOX15 (0.63) ALOX15BLMPMP22KMT2A
SCHEMBL5082336 0.77 ALOX15 (0.67) ALOX15BLMPMP22KMT2A
SCHEMBL2351136 0.77 ALOX15 (0.50) ALOX15BLMPMP22KMT2A
SCHEMBL1537476 0.77 ALOX15 (0.67) ALOX15BLMPMP22KMT2A
SCHEMBL6858574 0.76 GPR174 (0.44) ALOX15BLMPMP22KMT2AP2RY10
Glutamine SCHEMBL7559917 0.76 ALOX15 (0.70) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL2351130 0.75 ALOX15 (0.83) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL2351128 0.75 ALOX15 (0.83) ALOX15BLMPMP22KMT2A
SCHEMBL28919279 0.74 ALOX15 (0.47) ALOX15BLMPMP22KMT2A
Serine SCHEMBL9716102 0.74 ALOX15 (0.56) ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6803203-B1 PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS BROOKHAVEN SCIENCE ASSOCIATES 2004-10-12 US disclosed