Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310717 | 0.86 | HDAC1 (0.49) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL20178649 | 0.86 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL17262947 | 0.84 | POLB (0.51) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL29647869 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL20021588 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL6850945 | 0.82 | HDAC1 (0.44) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL18593240 | 0.79 | GAA (0.54) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL20178650 | 0.79 | ACHE (0.54) | ALDH1A1GAAMAPTCASP1HTT | |
| SCHEMBL1311927 | 0.77 | HDAC1 (0.53) | ALDH1A1GAAMAPTTSHRKDM4E | |
| SCHEMBL7096495 | 0.77 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTCASP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828159-B1 | Carbopyronine fluorescent dyes | Drexhage, Karl-Heinz (DE) | 2004-12-07 | — | — | US | disclosed |
| EP-1173519-B1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL-HEINZ (DE) | 2003-08-20 | — | — | EP | disclosed |
| EP-1173519-A1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE, Karl-Heinz (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064986-A1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL HEINZ (DE) | 2000-11-02 | — | — | WO | disclosed |