Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645348 | 0.91 | HRH3 (0.47) | ALDH1A1GAAMAPTALOX15TSHR | |
| SCHEMBL7093451 | 0.84 | HRH3 (0.39) | ALDH1A1MAPTTSHRHRH3KMT2A | |
| SCHEMBL6649352 | 0.79 | HRH3 (0.47) | ALDH1A1MAPTSMN1; SMN2HRH3KMT2A | |
| SCHEMBL29647869 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTALOX15TSHR | |
| SCHEMBL20021588 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTALOX15TSHR | |
| SCHEMBL12495697 | 0.77 | HRH3 (0.43) | ALDH1A1GAAMAPTALOX15TSHR | |
| SCHEMBL6858751 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTALOX15TSHR | |
| SCHEMBL22140444 | 0.74 | KMT2A (0.47) | ALDH1A1GAAMAPTALOX15TSHR | |
| SCHEMBL19603145 | 0.73 | HRH3 (0.51) | ALDH1A1HRH3KMT2AMEN1CHRM2 | |
| SCHEMBL11842202 | 0.73 | HRH3 (0.51) | ALDH1A1MAPTHTTHRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173519-B1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL-HEINZ (DE) | 2003-08-20 | — | — | EP | disclosed |
| EP-1173519-A1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE, Karl-Heinz (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064986-A1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL HEINZ (DE) | 2000-11-02 | — | — | WO | disclosed |