Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | PDE1A | P54750 | 3/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.33 |
| ▸ | GCK | P35557 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325939 | 0.90 | KMT2A (0.37) | KMT2APDE1APDE1BPDE1CGCK | |
| SCHEMBL6328601 | 0.87 | KMT2A (0.33) | KMT2AGCKMAPTKDM4EALDH1A1 | |
| SCHEMBL7548040 | 0.83 | GCK (0.39) | PDE1APDE1BPDE1CGCKPDE5A | |
| SCHEMBL7548038 | 0.81 | KDM4C (0.41) | KMT2APDE1APDE1BPDE1CGCK | |
| SCHEMBL7214537 | 0.77 | SIGMAR1 (0.43) | KMT2AGCKSMN1; SMN2KDM4EPDE5A | |
| SCHEMBL7214535 | 0.75 | KMT2A (0.36) | KMT2AGCKNPC1RAB9AMEN1 | |
| SCHEMBL10671194 | 0.74 | KMT2A (0.51) | CYP3A4CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL7541012 | 0.74 | ALDH1A1 (0.39) | KMT2AGCKSMN1; SMN2MAPTRAB9A | |
| SCHEMBL7541006 | 0.73 | ALDH1A1 (0.32) | CYP2D6KMT2AGCKSMN1; SMN2MAPT | |
| SCHEMBL6330868 | 0.72 | GCK (0.32) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229358-C | Novel tetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 2005-11-30 | — | — | CN | disclosed |
| US-6790810-B2 | Tetrazolinone derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 2004-09-14 | — | — | US | disclosed |
| US-6624121-B1 | Exemplified by 2-cyano-3-cyclopropyl-1-(3-((4-cyclopropyl-4,5-dihydro-5-oxo-1H-tetrazol-1 -yl)methyl)-2, 4-dichlorophenyl)propan-1,3-dione | NIHON BAYER AGROCHEM K.K. (JP) | 2003-09-23 | — | — | US | disclosed |
| CN-1370153-A | Herbicidal tetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 2002-09-18 | — | — | CN | disclosed |