SCHEMBL7541006

SCHEMBL7541006

CCn1nccc1OCc1ccc(Cn2nnn(C3CC3)c2=O)cc1[N+](=O)[O-]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.32
CYP2D6 P10635 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PDCD1 Q15116 3/20 0.32
CD274 Q9NZQ7 3/20 0.32
HTT P42858 3/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
GCK P35557 1/20 0.31
KDM5A P29375 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
KDM5B Q9UGL1 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7548038 0.87 KDM4C (0.41) POLBGCKKDM5AKDM4CKDM5B
SCHEMBL7541012 0.86 ALDH1A1 (0.39) ALDH1A1HTTMAPTRAB9APKM
SCHEMBL6328601 0.83 KMT2A (0.33) ALDH1A1L3MBTL1HTTMAPTKDM4E
SCHEMBL7214537 0.75 SIGMAR1 (0.43) KDM4EPOLBSMN1; SMN2LMNAGCK
SCHEMBL5906209 0.74 NR3C1 (0.39) ALDH1A1L3MBTL1MAPTKDM4EPOLB
SCHEMBL6858795 0.73 CYP3A4 (0.34) ALDH1A1CYP2D6MAPTRAB9AKDM4E
SCHEMBL5906192 0.70 HPGD (0.40) ALDH1A1L3MBTL1HTTMAPTRAB9A
SCHEMBL5906039 0.64 MAPT (0.39) ALDH1A1L3MBTL1MAPTLMNAKMT2A
SCHEMBL6274655 0.63 ADORA2A (0.38) ALDH1A1HTTMAPTKDM4EPOLB
SCHEMBL14491895 0.63 ADORA2A (0.36) ALDH1A1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208090-A1 HERBICIDALTETRAZOLINONE DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 2002-05-29 EP disclosed
WO-2001010850-A1 HERBICIDAL TETRAZOLINONE DERIVATIVES NIHON BAYER AGROCHEM K.K. (DE) 2001-02-15 WO disclosed