Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 9/20 | 0.39 |
| ▸ | PDE5A | O76074 | 4/20 | 0.39 |
| ▸ | PDE1A | P54750 | 4/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214537 | 0.90 | SIGMAR1 (0.43) | GCKPDE5ASIGMAR1 | |
| SCHEMBL7541012 | 0.86 | ALDH1A1 (0.39) | GCK | |
| SCHEMBL7548038 | 0.85 | KDM4C (0.41) | GCKPDE5APDE1APDE1BPDE1C | |
| SCHEMBL6858795 | 0.83 | CYP3A4 (0.34) | GCKPDE5APDE1APDE1BPDE1C | |
| SCHEMBL7214535 | 0.80 | KMT2A (0.36) | GCKSIGMAR1 | |
| SCHEMBL7541006 | 0.75 | ALDH1A1 (0.32) | GCK | |
| SCHEMBL6328601 | 0.74 | KMT2A (0.33) | GCK | |
| SCHEMBL6274655 | 0.67 | ADORA2A (0.38) | PDE5APDE1APDE1BPDE1CSIGMAR1 | |
| SCHEMBL14491895 | 0.67 | ADORA2A (0.36) | — | |
| SCHEMBL7540915 | 0.66 | GCK (0.33) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208090-A1 | HERBICIDALTETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010850-A1 | HERBICIDAL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2001-02-15 | — | — | WO | disclosed |