⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432734 | 0.80 | PTPRC (0.35) | — | |
| SCHEMBL2053601 | 0.78 | CA1 (0.35) | — | |
| SCHEMBL2433233 | 0.77 | EIF4E (0.34) | — | |
| SCHEMBL435279 | 0.73 | CYP1A2 (0.38) | — | |
| SCHEMBL15637773 | 0.72 | GABRG2 (0.42) | — | |
| SCHEMBL5584101 | 0.72 | IDO1 (0.32) | — | |
| SCHEMBL39183 | 0.72 | — | — | |
| SCHEMBL3991 | 0.72 | — | — | |
| SCHEMBL15637652 | 0.72 | GPR3 (0.32) | — | |
| SCHEMBL2050955 | 0.71 | PTGS2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3032 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239755-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-07-18 | — | — | US | claimed |
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| EP-3702354-B1 | COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF | HAIHE BIOPHARMA CO LTD (CN) | 2024-05-22 | — | — | EP | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| WO-2024092185-A1 | ACYL SULFONAMIDE COMPOUNDS AS INHIBITORS OF POLYOMAVIRUS | VIA NOVA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| EP-4345101-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2024-04-03 | — | — | EP | claimed |
| CN-111527099-B | Selective inhibitors of protein arginine methyltransferase 5 (PRMT 5) | 普莱鲁德疗法有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-4330234-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-03-06 | — | — | EP | claimed |
| EP-3615527-B1 | NEW AZAQUINOLINE DERIVATIVES | ELANCO ANIMAL HEALTH GMBH (DE) | 2024-03-06 | — | — | EP | claimed |
| US-4567174-A | BACTERICIDES, FUNGICIDES, CONTRACEPTIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-28 | — | — | US | claimed |
| EP-0168151-A1 | Dihydropyridine cardiovascular agents | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | claimed |
| US-4559350-A | Antihypertensive tetrahydropyridine 3-cyano 5-carboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | claimed |
| US-4512989-A | IMIDOESTERS OR IMIDOTHIOESTERS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 1985-04-23 | — | — | US | claimed |
| EP-0126567-A1 | Bis(1-substituted biguanide) derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-28 | — | — | EP | claimed |
| EP-0125827-A1 | Polyether bisbiguanides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-21 | — | — | EP | claimed |
| EP-0125092-A1 | Bisbiguanide compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0110073-A1 | Process for the preparation of tetrahydropyridines | BAYER AG (DE) | 1984-06-13 | — | — | EP | claimed |
| US-4391804-A | Imidazole derivatives and fungicidal composition containing the same | HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1983-07-05 | — | — | US | claimed |
| US-4224052-A | Polysubstituted butanoic acids, esters and derivatives thereof utilizing the same as herbicides | AMERICAN CYANAMID COMPANY (US) | 1980-09-23 | — | — | US | claimed |