Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 5/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864541 | 0.84 | PAOX (0.46) | PAOXKDM4EDNM1TDP1ALDH1A1 | |
| SCHEMBL17181018 | 0.81 | PAOX (0.43) | PAOXKDM4EDNM1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29083385 | 0.79 | KDM4E (0.44) | PAOXKDM4EDNM1TDP1ALDH1A1 | |
| SCHEMBL427283 | 0.77 | KDM4E (0.61) | PAOXKDM4EDNM1ALDH1A1MEN1 | |
| SCHEMBL28810241 | 0.75 | ALDH1A1 (0.53) | PAOXKDM4EDNM1TDP1ALDH1A1 | |
| SCHEMBL4864289 | 0.74 | — | — | |
| SCHEMBL7705371 | 0.73 | HDAC1 (0.49) | PAOXKDM4EALDH1A1TSHR | |
| SCHEMBL9813294 | 0.72 | TDP1 (0.42) | PAOXDNM1TDP1ALDH1A1HPGD | |
| SCHEMBL29244184 | 0.72 | ALDH1A1 (0.44) | PAOXKDM4EDNM1TDP1ALDH1A1 | |
| SCHEMBL13260105 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835757-B2 | Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. | 2004-12-28 | — | — | US | disclosed |