Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10855029 | 0.87 | CA1 (0.43) | TDP1CA1CA2CA12CA9 | |
| SCHEMBL17181018 | 0.79 | PAOX (0.43) | TDP1ALDH1A1HSD17B10HPGDCYP2C9 | |
| SCHEMBL29244184 | 0.79 | ALDH1A1 (0.44) | TDP1ALDH1A1HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL532919 | 0.78 | TDP1 (0.45) | TDP1CA1CA2CA12CA9 | |
| Bromide SCHEMBL10340652 | 0.78 | HRH4 (0.46) | TDP1ALDH1A1HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL721193 | 0.76 | — | — | |
| SCHEMBL41078 | 0.74 | ALDH1A1 (0.40) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7864541 | 0.74 | PAOX (0.46) | TDP1ALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL28810241 | 0.74 | ALDH1A1 (0.53) | TDP1CA2CA12CA9ALDH1A1 | |
| SCHEMBL6859040 | 0.72 | PAOX (0.48) | TDP1ALDH1A1HPGDPAOXTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191948-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-31 | — | — | EP | disclosed |
| US-4696894-A | Silver halide photographic materials containing 1,3,4-thiadiazole derivatives having a polar substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-29 | — | — | US | disclosed |
| EP-0191948-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1986-08-27 | — | — | EP | disclosed |