SCHEMBL7864541

SCHEMBL7864541

CN(C)CCCNNC(=O)NNCCCN(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.46
DNM1 Q05193 2/20 0.43
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
PRMT3 O60678 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT1 Q99873 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.38
HPGD P15428 1/20 0.38
KDM4A O75164 2/20 0.36
KDM4C Q9H3R0 2/20 0.36
ANPEP P15144 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6859040 0.84 PAOX (0.48) PAOXDNM1TDP1KDM4EALDH1A1
SCHEMBL17181018 0.83 PAOX (0.43) PAOXDNM1TDP1KDM4EALDH1A1
SCHEMBL4258818 0.78 TDP1 (0.48) PAOXDNM1TDP1KDM4EALDH1A1
SCHEMBL28810241 0.77 ALDH1A1 (0.53) PAOXDNM1TDP1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL29083385 0.77 KDM4E (0.44) PAOXDNM1TDP1KDM4EALDH1A1
SCHEMBL36169 0.76 DNM1 (0.55) PAOXDNM1KDM4EALDH1A1MEN1
Hydrochloric Acid SCHEMBL10730965 0.74 DNM1 (0.53) PAOXDNM1KDM4EALDH1A1MEN1
SCHEMBL29244184 0.74 ALDH1A1 (0.44) PAOXDNM1TDP1KDM4EALDH1A1
SCHEMBL9813294 0.74 TDP1 (0.42) PAOXDNM1TDP1ALDH1A1PRMT3
SCHEMBL24102742 0.73 DNM1 (0.52) PAOXDNM1KDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313346-B1 Catalyst compositions for the production of polyurethanes AIR PRODUCTS AND CHEMICALS, INC. 2001-11-06 US disclosed
US-6153659-A 3-{N-[2-(N',N'-dimethylamino ethoxy)ethyl]-N-methylamino}propionamide for the production of polyurethanes AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-11-28 US disclosed
US-6037496-A CATALYZES THE REACTION BETWEEN AN ISOCYANATE AND WATER IN THE PRODUCTION OF FOAMED POLYURETHANES AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-03-14 US disclosed