SCHEMBL6859273

SCHEMBL6859273

C[Si](C)(C)N(C1CCCCC1)[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 8/20 0.39
ADH1C P00326 5/20 0.39
PHGDH O43175 2/20 0.34
ADH1B P00325 1/20 0.34
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
S1PR3 Q99500 2/20 0.32
GAA P10253 1/20 0.32
ADH4 P08319 1/20 0.31
S1PR1 P21453 1/20 0.31
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857821 0.97 ADH1A (0.35) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL22287345 0.78 ADH1A (0.36) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL28594750 0.74 ADH1A (0.42) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL22287316 0.74 ADH1A (0.32) ADH1AADH1C
SCHEMBL28855464 0.69 ADH1C (0.31) ADH1AADH1C
SCHEMBL6567110 0.69 ADH1A (0.43) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL79286 0.69 ADH1A (0.43) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL16974433 0.69 ADH1A (0.43) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL9551174 0.67 ADH1A (0.52) ADH1AADH1CPHGDHADH1BFAAH
SCHEMBL18841464 0.67 ADH1A (0.52) ADH1AADH1CPHGDHADH1BFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140275418-A1 Method and substrate for covalent attachment and encapsulation of biological, chemical and physical substances Dyanov, Hristem Mitkov (US) 2014-09-18 US disclosed
US-6737193-B2 ACTIVE MATERIALS IN THE POSITIVE ELECTRODES OF BATTERIES. NOVEL METHODS FOR PREPARING THE TETRAKETOPIPERAZINE UNIT-CONTAINING COMPOUNDS INCLUDE: (I) REACTING AN OXALYL HALIDE AND AN OXAMIDE, AND ADDING WATER OR AN AQUEOUS ALKALI IM&T RESEARCH, INC. 2004-05-18 US disclosed
US-20030148188-A1 Active materials in the positive electrodes of batteries. Novel methods for preparing the tetraketopiperazine unit-containing compounds include: (i) reacting an oxalyl halide and an oxamide, and adding water or an aqueous alkali IM&T RESEARCH, INC. 2003-08-07 US disclosed