Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 10/20 | 0.43 |
| ▸ | GSK3B | P49841 | 10/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860968 | 0.80 | GSK3A (0.44) | GSK3AGSK3BPIK3CGPIK3CAMEN1 | |
| SCHEMBL1116168 | 0.72 | CA2 (0.42) | PIK3CGPIK3CAMEN1KMT2AL3MBTL1 | |
| SCHEMBL1116169 | 0.72 | CA2 (0.42) | PIK3CGPIK3CAMEN1KMT2AL3MBTL1 | |
| SCHEMBL6858664 | 0.72 | GSK3A (0.74) | GSK3AGSK3BMEN1KMT2AL3MBTL1 | |
| SCHEMBL6858213 | 0.71 | GSK3B (0.39) | GSK3AGSK3BPIK3CGPIK3CAMEN1 | |
| SCHEMBL1115920 | 0.69 | CYP2E1 (0.54) | PIK3CGPIK3CAMEN1KMT2AL3MBTL1 | |
| SCHEMBL621836 | 0.63 | PIK3CG (0.78) | GSK3AGSK3BPIK3CGPIK3CAMEN1 | |
| SCHEMBL621835 | 0.63 | PIK3CG (0.78) | GSK3AGSK3BPIK3CGPIK3CAMEN1 | |
| SCHEMBL3362480 | 0.61 | GSK3A (0.77) | GSK3AGSK3BMEN1KMT2AL3MBTL1 | |
| SCHEMBL12990390 | 0.61 | GSK3A (0.77) | GSK3AGSK3BMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011015646-A2 | FURAN-IMIDAZOLONE DERIVATIVES, FOR THE TREATMENT OF COGNITIVE, NEURODEGENERATIVE OR NEURONAL DISEASES OR DISORDERS | NOSCIRA, S.A. (ES) | 2011-02-10 | — | — | WO | disclosed |
| EP-2281824-A1 | Furan-imidazolone derivatives, for the treatment of cognitive, neurodegenerative or neuronal diseases or disorders | NOSCIRA, S.A. (ES) | 2011-02-09 | — | — | EP | disclosed |