Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866676 | 0.90 | SHBG (0.51) | SHBGGAATP53ESR2MAOB | |
| SCHEMBL27567023 | 0.87 | KCNA2 (0.42) | TP53MAOBKCNA2KCNA5KCNA1 | |
| SCHEMBL6937223 | 0.85 | SHBG (0.55) | SHBGGAATP53ESR2MAOB | |
| SCHEMBL6860106 | 0.80 | SLC26A3 (0.37) | TP53MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL27500090 | 0.72 | KCNA2 (0.47) | GAAKCNA2KCNA5KCNA1MAPT | |
| SCHEMBL24045237 | 0.72 | GAA (0.55) | SHBGGAATP53ESR2MAPT | |
| SCHEMBL6870370 | 0.71 | MAOB (0.41) | SHBGGAATP53ESR2MAOB | |
| SCHEMBL6867274 | 0.70 | NPC1 (0.40) | TP53MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL27517970 | 0.69 | ALDH1A1 (0.53) | GAAESR2MAOBMAPTKDM4E | |
| SCHEMBL1590178 | 0.66 | KMT2A (0.52) | GAAKCNA2KCNA5KCNA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308342-C | Ribose-substituted aromatic compounds, process for their preparation and their use as medicaments | AVENTIS PHARMA SA (FR) | 2007-04-04 | — | — | CN | disclosed |
| US-6812331-B2 | BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2004-11-02 | — | — | US | disclosed |
| US-6350733-B1 | 4-HYDROXYBENZOPYRAN-2-ONE DERIVATIVES; BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS; SKIN DISORDERS | AVENTIS PHARMA S.A. (FR) | 2002-02-26 | — | — | US | disclosed |
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | AVENTIS PHARMA S.A. | 2002-01-24 | — | — | US | disclosed |
| CN-1227564-A | Novel aromatic compounds substituted by ribose, preparation method and application as medicine thereof | HOECHST MARION ROUSSEL INC (FR) | 1999-09-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | RPIA, CD38, PARP1 | SHBG 4806/4885GAA 183/4885TP53 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.