SCHEMBL6860102

SCHEMBL6860102

C[Si](C)(Cl)c1c2ccccc2c([Si](C)(C)Cl)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.36
CYP2A6 P11509 3/20 0.36
GPR3 P46089 3/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
MAOA P21397 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MAOB P27338 2/20 0.35
GLA P06280 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
PGAM1 P18669 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAPK1 P28482 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10318161 0.83 L3MBTL1 (0.45) CYP1A2CYP2A6ALDH1A1KDM4EMAOA
SCHEMBL15087193 0.78 DHFR (0.45) CYP1A2CYP2A6ALDH1A1KDM4ESMN1; SMN2
SCHEMBL13295950 0.75 CYP2C19 (0.33) ALDH1A1KDM4ECYP2C19TSHR
SCHEMBL12627474 0.75 CYP1A2 (0.40) CYP1A2CYP2A6GPR3ALDH1A1KDM4E
SCHEMBL1459198 0.69 TSHR (0.32) ALDH1A1MAPTTSHRTDP1
SCHEMBL9291881 0.69 IDO1 (0.30)
SCHEMBL1315212 0.69 CYP2A6 (0.41) CYP1A2CYP2A6ALDH1A1SMN1; SMN2TSHR
SCHEMBL10319492 0.67 CYP2A6 (0.44) CYP1A2CYP2A6ALDH1A1HSD17B10CYP3A4
SCHEMBL68909 0.67 ESR1 (0.44) ALDH1A1MAOASMN1; SMN2HSD17B10MAOB
SCHEMBL4586361 0.65 CYP1A2 (0.32) CYP1A2GPR3ALDH1A1KDM4EMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7309882-A None JP disclosed
US-6709772-B2 SILICONE-PYRROLE COMPOUND MITSUMI ELECTRIC CO., LTD. (JP) 2004-03-23 US disclosed
US-20030087128-A1 Organic electrically conductive compound and an organic electroluminescent device including the compound MITSUMI ELECTRIC CO., LTD. (JP) 2003-05-08 US disclosed
JP-H07309882-A NEW ORGANOHALOSILANE COMPOUND TOAGOSEI CO LTD 1995-11-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087128-A1 Organic electrically conductive compound and an organic electroluminescent device including the compound KCNT1, KCNJ2, KCNA1 CYP1A2 968/4885CYP2A6 3219/4885GPR3 844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.