Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23319148 | 0.76 | PIM1 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29763176 | 0.75 | TRPA1 (0.70) | TRPA1CNR1CNR2POLBALOX5 | |
| SCHEMBL8047684 | 0.75 | TRPA1 (0.70) | TRPA1CNR1CNR2POLBALOX5 | |
| SCHEMBL30641040 | 0.73 | NISCH (0.36) | POLBALDH1A1GAANPC1RAB9A | |
| SCHEMBL12054574 | 0.71 | HSD17B1 (0.47) | ALOX5ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23318985 | 0.70 | TRPA1 (0.42) | TRPA1POLBALDH1A1MAPTGAA | |
| Sulfur Dioxide SCHEMBL20526202 | 0.69 | TRPA1 (0.59) | TRPA1CNR1CNR2POLBALOX5 | |
| SCHEMBL23986122 | 0.67 | TRPA1 (0.57) | TRPA1CNR1CNR2POLBALOX5 | |
| SCHEMBL25383045 | 0.67 | CNR1 (0.88) | TRPA1CNR1CNR2POLBALOX5 | |
| SCHEMBL4288864 | 0.67 | TRPA1 (0.57) | TRPA1CNR1CNR2POLBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028031-A2 | IN SITU-FORMING HYDROGEL FOR TISSUE ADHESIVES AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2011-03-10 | — | — | WO | disclosed |