Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639080 | 0.90 | LMNA (0.43) | LMNAADRB1SIRT6ALDH1A1POLB | |
| SCHEMBL9786136 | 0.90 | LMNA (0.43) | LMNAADRB1SIRT6ALDH1A1POLB | |
| SCHEMBL8127951 | 0.89 | ADRB1 (0.45) | LMNAADRB1SIRT6ALDH1A1POLB | |
| SCHEMBL8133139 | 0.89 | ADRB1 (0.45) | LMNAADRB1SIRT6ALDH1A1POLB | |
| Oxalic Acid SCHEMBL522460 | 0.84 | ALDH1A1 (0.41) | LMNAADRB1SIRT6ALDH1A1POLB | |
| SCHEMBL10922465 | 0.83 | LMNA (0.50) | LMNAALDH1A1POLBRECQLCRYZ | |
| SCHEMBL25230818 | 0.82 | LMNA (0.44) | LMNAADRB1SIRT6ALDH1A1POLB | |
| SCHEMBL29116544 | 0.82 | LMNA (0.44) | LMNAADRB1SIRT6ALDH1A1POLB | |
| SCHEMBL11631660 | 0.81 | SLC6A3 (0.47) | LMNAALDH1A1POLBSLC6A3RECQL | |
| Pyridine SCHEMBL28226947 | 0.80 | LMNA (0.37) | LMNAADRB1SIRT6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825189-B1 | TREATING WITHDRAWAL SYMPTOMS CAUSED BY SMOKING CESSATION | NEUROSEARCH A/S (DK) | 2004-11-30 | — | — | US | claimed |