Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7104426 | 0.83 | KCNK18 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7107702 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7092701 | 0.80 | POLB (0.32) | POLB | |
| Hydrochloric Acid SCHEMBL6830301 | 0.80 | FFAR4 (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL5853068 | 0.80 | HDAC3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6702088 | 0.79 | KMT2A (0.34) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL6827117 | 0.79 | POLB (0.34) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL5855900 | 0.77 | POLB (0.37) | MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL6865136 | 0.77 | ACHE (0.39) | — | |
| Hydrochloric Acid SCHEMBL6914406 | 0.77 | GPR3 (0.33) | MEN1POLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |