Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6702088 | 0.87 | KMT2A (0.34) | POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL7092701 | 0.81 | POLB (0.32) | POLBLPAR1 | |
| Hydrochloric Acid SCHEMBL6861247 | 0.79 | MEN1 (0.30) | POLBKMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL5855851 | 0.78 | BCL2 (0.36) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5853618 | 0.77 | LMNA (0.36) | KMT2A | |
| Hydrochloric Acid SCHEMBL7107702 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5853633 | 0.75 | KMT2A (0.35) | POLBL3MBTL1KMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL6830301 | 0.73 | FFAR4 (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL6865136 | 0.70 | ACHE (0.39) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5855900 | 0.70 | POLB (0.37) | POLBL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |