Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 14/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194228 | 0.81 | ALOX15 (0.36) | ALOX15TSHRCYP19A1 | |
| SCHEMBL30515432 | 0.81 | ALOX15 (0.36) | ALOX15TSHRCYP19A1 | |
| SCHEMBL12812311 | 0.70 | TSHR (0.36) | TSHRCYP19A1 | |
| SCHEMBL17204821 | 0.68 | — | — | |
| SCHEMBL17213193 | 0.68 | — | — | |
| SCHEMBL19621509 | 0.67 | TSHR (0.38) | TSHR | |
| SCHEMBL6861304 | 0.67 | TSHR (0.37) | OPRK1ALOX15TSHRCYP19A1 | |
| SCHEMBL19621415 | 0.66 | TSHR (0.36) | TSHR | |
| SCHEMBL3707344 | 0.66 | TSHR (0.36) | TSHR | |
| SCHEMBL13255134 | 0.66 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069123-B1 | PROCESS FOR PRODUCING BENZOTHIOPHENECARBOXYLIC ACID AMIDE DERIVATIVES | SHIONOGI & CO (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20020161242-A1 | Process for preparing benzothiophenecarboxamide derivatives | HONMA TSUNETOSHI (JP) | 2002-10-31 | — | — | US | disclosed |
| US-20020156297-A1 | Process for preparing benzothiophenecarboxamide derivatives | OKADA TETSUO (JP) | 2002-10-24 | — | — | US | disclosed |
| US-6399788-B1 | AMIDATION | SHIONOGI & CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161242-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | OPRK1 515/4885ALOX15 223/4885TSHR 1965/4885 |
| US-20020156297-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | OPRK1 515/4885ALOX15 223/4885TSHR 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.