Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861342 | 0.88 | GRIA2 (0.54) | GRIA2CYP2D6CYP1A2POLBMAPT | |
| SCHEMBL6861147 | 0.87 | ABHD6 (0.48) | POLBMAPTTP53LMNA | |
| SCHEMBL6861702 | 0.87 | MAPT (0.43) | GRIA2CYP1A2POLBMAPTCYP2C19 | |
| SCHEMBL6864318 | 0.85 | KDM4E (0.44) | GRIA2POLBMAPTLMNAALDH1A1 | |
| SCHEMBL1007660 | 0.84 | GRIA2 (0.57) | GRIA2CYP2D6CYP1A2POLBMAPT | |
| SCHEMBL6860475 | 0.78 | LMNA (0.44) | GRIA2CYP1A2POLBMAPTCYP2C9 | |
| SCHEMBL6860844 | 0.75 | CYP2C19 (0.43) | GRIA2CYP2D6CYP1A2POLBMAPT | |
| SCHEMBL1006841 | 0.75 | POLB (0.51) | GRIA2CYP2D6CYP1A2POLBMAPT | |
| SCHEMBL12998713 | 0.75 | GRIA2 (0.69) | GRIA2CYP2D6CYP1A2MAPTCYP2C9 | |
| SCHEMBL1006269 | 0.74 | GRIA2 (0.55) | GRIA2CYP2D6CYP1A2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |