Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 7/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861498 | 0.88 | GRIA2 (0.44) | GRIA2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6860475 | 0.87 | LMNA (0.44) | GRIA2CYP1A2CYP2C9CYP2C19POLQ | |
| SCHEMBL6860844 | 0.84 | CYP2C19 (0.43) | GRIA2CYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL12998713 | 0.82 | GRIA2 (0.69) | GRIA2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6862770 | 0.82 | SMN1; SMN2 (0.39) | GRIA2CYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL6861147 | 0.77 | ABHD6 (0.48) | MAPTPOLBTP53LMNATSHR | |
| SCHEMBL6861702 | 0.77 | MAPT (0.43) | GRIA2CYP1A2CYP2C19MAPTPOLB | |
| SCHEMBL6864318 | 0.75 | KDM4E (0.44) | GRIA2MAPTPOLBLMNANPSR1 | |
| SCHEMBL12997891 | 0.74 | GRIA2 (0.74) | GRIA2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15491619 | 0.74 | LMNA (0.48) | GRIA2CYP1A2CYP2C19POLQMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |