SCHEMBL6861774

SCHEMBL6861774

C=C(C)C(=O)OC(C)[N+](C)(CCCCCCCCCCCC)C(C)OC(=O)C(=C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.47
LMNA P02545 5/20 0.38
MAPT P10636 6/20 0.36
MAPK1 P28482 5/20 0.36
MEN1 O00255 3/20 0.35
GMNN O75496 3/20 0.35
KMT2A Q03164 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
TP53 P04637 3/20 0.35
CYP1A2 P05177 2/20 0.35
HSP90AA1 P07900 2/20 0.35
BLM P54132 2/20 0.35
NR1H4 Q96RI1 2/20 0.35
CYP2C9 P11712 2/20 0.35
HIF1A Q16665 2/20 0.35
FAAH O00519 1/20 0.35
CYP2D6 P10635 2/20 0.35
GLA P06280 1/20 0.35
PMP22 Q01453 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6861701 0.98 TSHR (0.50) TSHRLMNAMAPTMAPK1MEN1
SCHEMBL9772649 0.88 TSHR (0.47) TSHRLMNAMAPTMAPK1MEN1
SCHEMBL27943905 0.88 TSHR (0.47) TSHRLMNAMAPTMAPK1MEN1
Hydrochloric Acid SCHEMBL28421869 0.86 TSHR (0.50) TSHRLMNAMAPTMAPK1MEN1
Bromide SCHEMBL11689756 0.86 TSHR (0.46) TSHRLMNAMAPTTP53HSP90AA1
Bromide SCHEMBL23923504 0.86 TSHR (0.46) TSHRLMNAMAPTTP53HSP90AA1
Bromide SCHEMBL28483715 0.86 TSHR (0.46) TSHRLMNAMAPTTP53HSP90AA1
Bromide SCHEMBL28559975 0.86 TSHR (0.46) TSHRLMNAMAPTTP53HSP90AA1
Bromide SCHEMBL7117275 0.86 TSHR (0.46) TSHRLMNAMAPTTP53HSP90AA1
Bromide SCHEMBL28443842 0.86 TSHR (0.46) TSHRLMNAMAPTTP53HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055449-A1 FUNCTIONAL SURFACES ORTHOBOND CORP (US) 2023-02-23 US claimed
EP-3525776-B1 SURFACES WITH OLIGOMERIC OR POLYMERIC ANTIMICROBIALS ORTHOBOND CORP (US) 2022-01-26 EP claimed
US-20210352903-A1 FUNCTIONAL SURFACES ORTHOBOND CORP (US) 2021-11-18 US claimed
US-11154061-B2 Functional surfaces Orthobond Corporation (US) 2021-10-26 US claimed
US-10390533-B2 Surfaces with oligomeric or polymeric antimicrobials Orthobond Corporation (US) 2019-08-27 US claimed
EP-3525776-A1 SURFACES WITH OLIGOMERIC OR POLYMERIC ANTIMICROBIALS Orthobond Corporation (US) 2019-08-21 EP claimed
WO-2018075457-A1 SURFACES WITH OLIGOMERIC OR POLYMERIC ANTIMICROBIALS Orthobond Corporation (US) 2018-04-26 WO claimed
US-20180103643-A1 Functional Surfaces Orthobond Corporation 2018-04-19 US claimed
US-20180103642-A1 Surfaces with Oligomeric or Polymeric Antimicrobials Orthobond Corporation 2018-04-19 US claimed
US-20230055449-A1 FUNCTIONAL SURFACES ORTHOBOND CORP (US) 2023-02-23 US disclosed
WO-2022182713-A1 METHODS OF PHOTOGRAFTING TO SURFACE METAL OXIDES Orthobond Corporation (US) 2022-09-01 WO disclosed
US-20220266296-A1 Methods of Photografting to Surface Metal Oxides Orthobond Corporation 2022-08-25 US disclosed
EP-3525776-B1 SURFACES WITH OLIGOMERIC OR POLYMERIC ANTIMICROBIALS ORTHOBOND CORP (US) 2022-01-26 EP disclosed
US-20210352903-A1 FUNCTIONAL SURFACES ORTHOBOND CORP (US) 2021-11-18 US disclosed
US-20180103642-A1 Surfaces with Oligomeric or Polymeric Antimicrobials Orthobond Corporation 2018-04-19 US disclosed
US-6790877-B2 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2004-09-14 US disclosed
EP-0980682-B1 Bonding compositions for dental use KURARAY CO (JP) 2003-11-05 EP disclosed
US-20020035169-A1 Bonding compositions for dental use KURARAY CO., LTD (JP) 2002-03-21 US disclosed
US-6355704-B1 BACTERICIDE PRIMERS; BONDING TO TEETH KURARAY CO., LTD. (JP) 2002-03-12 US disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035169-A1 Bonding compositions for dental use PTK2, DEK, POLK TSHR 4726/4885LMNA 2015/4885MAPT 2574/4885
US-20180103642-A1 Surfaces with Oligomeric or Polymeric Antimicrobials PICALM, NONO, LPO TSHR 1455/4885LMNA 4563/4885MAPT 3100/4885
US-20230055449-A1 FUNCTIONAL SURFACES LPO, SELP, SIGLEC7 TSHR 2514/4885LMNA 3860/4885MAPT 3662/4885
US-11154061-B2 Functional surfaces LPO, SELP, SIGLEC7 TSHR 2514/4885LMNA 3860/4885MAPT 3662/4885
US-20210352903-A1 FUNCTIONAL SURFACES LPO, SELP, SIGLEC7 TSHR 2514/4885LMNA 3860/4885MAPT 3662/4885
US-10390533-B2 Surfaces with oligomeric or polymeric antimicrobials PICALM, NONO, LPO TSHR 1455/4885LMNA 4563/4885MAPT 3100/4885
US-20180103643-A1 Functional Surfaces LPO, SELP, SIGLEC7 TSHR 2514/4885LMNA 3860/4885MAPT 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.