Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 2/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862882 | 1.00 | LMNA (0.40) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6321164 | 0.84 | LMNA (0.38) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6322120 | 0.84 | LMNA (0.38) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6630215 | 0.82 | HTR1A (0.40) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6631890 | 0.82 | HTR1A (0.40) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6631298 | 0.80 | DRD2 (0.43) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4361994 | 0.80 | DRD2 (0.43) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6196047 | 0.80 | DRD2 (0.43) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4368745 | 0.80 | LMNA (0.40) | LMNAALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL5103551 | 0.80 | LMNA (0.40) | LMNAALDH1A1CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800648-B2 | SCHIZOPHRENIA, BIPOLAR DISORDERS, PARKINSON'S DISEASE; DRUG ABRUSE | WYETH | 2004-10-05 | — | — | US | disclosed |
| US-20030073697-A1 | Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one | WYETH | 2003-04-17 | — | — | US | disclosed |
| WO-2002088142-A1 | ANTIPSYCHOTIC AMINOMETHYL DERIVATIVES OF 7,8-DIHYDRO-3H-1,6,9-TRIOXA-3-AZA-CYCLOPENTA[a]NAPHTHALEN-2-ONE | WYETH (US) | 2002-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073697-A1 | Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one | SNCA, TUBA1C, SLC6A3 | LMNA 4322/4885ALDH1A1 1985/4885CYP3A4 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.