Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915818 | 0.87 | MAPT (0.77) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL2397324 | 0.87 | GAA (0.77) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL17899112 | 0.84 | ALDH1A1 (0.83) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL2397574 | 0.78 | MAPT (0.64) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL1914809 | 0.78 | GAA (0.64) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL6861634 | 0.76 | ALDH1A1 (0.77) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL17899118 | 0.74 | ALDH1A1 (0.74) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL5576161 | 0.74 | ALDH1A1 (0.72) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL5574964 | 0.73 | ALDH1A1 (0.71) | GAAMAPTALDH1A1HTTKDM4E | |
| SCHEMBL5574968 | 0.73 | ALDH1A1 (0.71) | GAAMAPTALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452590-A1 | STEREOSTRUCTURE OF DNA RECOMBINATION REPAIR ENZYME AND UTILIZATION THEREOF | Riken (JP) | 2004-09-01 | — | — | EP | disclosed |