Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167439 | 0.83 | FURIN (0.43) | HDAC6 | |
| SCHEMBL8761571 | 0.81 | CES2 (0.60) | CES2CES1PARP1PTGS1PTGS2 | |
| SCHEMBL28863383 | 0.81 | CES2 (0.60) | CES2CES1PARP1PTGS1PTGS2 | |
| SCHEMBL16230721 | 0.81 | CES2 (0.50) | CES2CES1PARP1PTGS1PTGS2 | |
| SCHEMBL6252421 | 0.80 | FURIN (0.41) | KDM4EALDH1A1 | |
| SCHEMBL17421702 | 0.80 | FURIN (0.41) | KDM4EALDH1A1 | |
| SCHEMBL30834584 | 0.80 | FURIN (0.41) | KDM4EALDH1A1 | |
| SCHEMBL6472416 | 0.79 | CES2 (0.70) | CES2CES1PARP1PTGS1PTGS2 | |
| SCHEMBL14537112 | 0.79 | CES2 (0.59) | CES2CES1PARP1PTGS1PTGS2 | |
| SCHEMBL27937666 | 0.79 | CES2 (0.59) | CES2CES1PARP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454136-A | Catalyst for catalyzing hydroformylation reaction of gem-disubstituted aromatic olefin and preparation method and application thereof | 中国科学院上海高等研究院 | 2020-07-28 | — | — | CN | claimed |
| CN-113788825-B | Heteroaromatic compounds as VANIN inhibitors | 勃林格殷格翰国际有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023189969-A1 | RESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN | 日本ゼオン株式会社 | 2023-10-05 | — | — | WO | disclosed |
| US-11644752-B2 | Polymer, positive resist composition, and method of forming resist pattern | ZEON CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| US-11644752-B2 | Polymer, positive resist composition, and method of forming resist pattern | ZEON CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| EP-3672952-B1 | BENZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |
| EP-3844161-B1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2022-11-09 | — | — | EP | disclosed |
| US-11215925-B2 | Method of forming resist pattern | ZEON CORPORATION (JP) | 2022-01-04 | — | — | US | disclosed |
| US-20210397097-A1 | METHOD OF PRODUCING MOLDED PRODUCT, RESIST FOR COLLECTIVE MOLDING WITH IMPRINT-ELECTRONIC LITHOGRAPHY, METHOD OF PRODUCING REPLICA MOLD, METHOD OF PRODUCING DEVICE, AND IMPRINT MATERIAL | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-12-23 | — | — | US | disclosed |
| CN-113788825-A | Heteroaromatic compounds as VANIN inhibitors | 勃林格殷格翰国际有限公司 | 2021-12-14 | — | — | CN | disclosed |
| WO-2014011429-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-01-16 | — | — | WO | disclosed |
| EP-2182002-A1 | Novel compounds for electronic material and organic electronic device using the same | Gracel Display Inc. (KR) | 2010-05-05 | — | — | EP | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| WO-2008005368-A2 | PIPERAZINES AS P2X7 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2008-01-10 | — | — | WO | disclosed |
| US-6800676-B2 | ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-05 | — | — | US | disclosed |
| EP-1305297-A1 | BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORP. | 2003-01-02 | — | — | US | disclosed |
| US-6451887-B1 | Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | disclosed |
| WO-2002012205-A1 | BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |
| EP-0435794-A1 | Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | CES2 411/4885CES1 330/4885PARP1 3529/4885 |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | SUV39H1, SUV39H2, TPST2 | CES2 1684/4885CES1 3530/4885PARP1 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.