Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014247 | 0.86 | LMNA (0.53) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL6014265 | 0.80 | LMNA (0.47) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL6014271 | 0.79 | LMNA (0.47) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL24961545 | 0.78 | LMNA (0.56) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL30952911 | 0.78 | LMNA (0.56) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL17384693 | 0.77 | LMNA (0.52) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL6014300 | 0.77 | LMNA (0.45) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL6014316 | 0.77 | LMNA (0.45) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL242405 | 0.77 | ALDH1A1 (0.50) | LMNATDP1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL6014276 | 0.77 | LMNA (0.44) | LMNATDP1HSD17B10SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453812-A2 | CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003041653-A2 | CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY (US) | 2003-05-22 | — | — | WO | disclosed |