Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.58 |
| ▸ | THRA | P10827 | 8/20 | 0.58 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | RXRA | P19793 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112243 | 0.80 | THRB (0.61) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL7112240 | 0.80 | THRB (0.61) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL1525945 | 0.78 | THRB (0.58) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL15500207 | 0.74 | THRB (0.54) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL3217395 | 0.74 | THRB (0.73) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL8196784 | 0.74 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL12764452 | 0.73 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL9522943 | 0.73 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| Thyroxine SCHEMBL26147 | 0.73 | THRB (1.00) | THRBTHRAPPARGMEN1KMT2A | |
| Thyroxine SCHEMBL4575383 | 0.73 | THRB (1.00) | THRBTHRAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265723-A | Novel monoclonal antibodies directed against L-thyroxine and diagnostic uses thereof | 豪夫迈·罗氏有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20040030365-A1 | Medical device to restore functions of a fibrillating heart by cardiac therapies remotely directed by a physician via two-way communication | RUBIN LEO (US) | 2004-02-12 | — | — | US | disclosed |
| EP-1339456-A2 | A MEDICAL DEVICE TO RESTORE FUNCTIONS OF A FIBRILLATING HEART BY CARDIAC THERAPIES REMOTELY DIRECTED BY A PHYSICIAN VIA TWO-WAY COMMUNICATION | Resuscitek, Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002045798-A2 | A MEDICAL DEVICE TO RESTORE FUNCTIONS OF A FIBRILLATING HEART BY CARDIAC THERAPIES REMOTELY DIRECTED BY A PHYSICIAN VIA TWO-WAY COMMUNICATION | RESUSCITEK, INC. (US) | 2002-06-13 | — | — | WO | disclosed |
| US-5168102-A | Administering thyroid hormone to decrease fat deposits | UNIVERSITY OF DELAWARE (US) | 1992-12-01 | — | — | US | disclosed |
| EP-0358754-A4 | ENDOCRINE MANIPULATION TO IMPROVE BODY COMPOSITION OF POULTRY | — | 1991-06-26 | — | — | EP | disclosed |
| US-4929600-A | THYROID HORMONES, ANTIFAT AGENTS | UNIVERSITY OF DELEWARE (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358754-A1 | ENDOCRINE MANIPULATION TO IMPROVE BODY COMPOSITION OF POULTRY | UNIVERSITY OF DELAWARE (US) | 1990-03-21 | — | — | EP | disclosed |
| WO-1989008458-A1 | ENDOCRINE MANIPULATION TO IMPROVE BODY COMPOSITION OF POULTRY | UNIVERSITY OF DELAWARE (US) | 1989-09-21 | — | — | WO | disclosed |