Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.61 |
| ▸ | THRA | P10827 | 10/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | RXRA | P19793 | 3/20 | 0.61 |
| ▸ | TTR | P02766 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112240 | 1.00 | THRB (0.61) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL6862911 | 0.80 | THRB (0.58) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL3217395 | 0.80 | THRB (0.73) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL18908564 | 0.77 | THRB (0.70) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL1526276 | 0.77 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL17612149 | 0.77 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL6995423 | 0.77 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL31542039 | 0.77 | MEP1B (0.40) | LMNAHSD17B10ALDH1A1MAPTPOLB | |
| SCHEMBL17612148 | 0.76 | THRB (0.68) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL30354491 | 0.76 | THRB (0.68) | THRBTHRAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032578-A1 | Antifungal and antiparasitic compounds | UNITED STATES GOVERNMENT | 2003-02-13 | — | — | US | disclosed |
| US-6403576-B1 | CHOLESTEROL SYNTHESIS INHIBITOR | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2002-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032578-A1 | Antifungal and antiparasitic compounds | PIGO, CAT, ERG28 | THRB 3884/4885THRA 4025/4885PPARG 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.